Weekly late-night show hosted by Hamada Masatoshi of Downtown along with a rotating guest MC. Each week is a different subject usually. Usually the episode is having a guest talent on to teach Hamada (Hamachan) about a certain subject, or going shopping with Hamada.
Talk Soup aired selected clips of the previous day's daily talk shows—ranging from daytime entries like The Jerry Springer Show and to celebrity interview shows like The Tonight Show—surrounded by humorous commentary delivered by the host. Although Talk Soup poked fun at the talk shows, it also advertised the topics and guests of upcoming broadcasts of them. Despite this several talk shows including The Oprah Winfrey Show refused to allow clips of their shows to be shown on the series. During its run, Talk Soup was nominated for five Daytime Emmy Awards, winning once in 1995 for Outstanding Special Class Program. It remains the only E! show to ever win an Emmy.
It includes different and entertaining segments that are held between two groups of well-known faces. Each group consists of a leader and a sibling who must be well-acquainted with each other's moral qualities so that they can overcome the various challenges of the competition and reach the final prize.