Mark Fallon, with partner Kansas John Polly, tries to introduce honest gambling on the riverboats. His first success makes enemies of the crooked gamblers and of fair Angelique Dureau, whose necklace he won. Later in New Orleans, Mark befriends Angelique's father, but she still affects to despise him as his gambling career brings him wealth. Duelling, tragedy, and romantic complications follow.
Unfortunately the movie The Mississippi Gambler is not yet available on HBO Max.
| Camera | Irving Glassberg | Director of Photography |
| Editing | Edward Curtiss | Editor |
| Sound | Frank Skinner | Music |
| Production | Ted Richmond | Producer |
| Writing | Seton I. Miller | Screenplay |
| Directing | Rudolph Maté | Director |
| Writing | Seton I. Miller | Story |
| Art | Alexander Golitzen | Art Direction |
| Art | Richard H. Riedel | Art Direction |
| Costume & Make-Up | Joan St. Oegger | Hairstylist |
| Sound | Richard DeWeese | Sound |
| Art | Julia Heron | Set Decoration |
| Directing | John Sherwood | Assistant Director |
| Costume & Make-Up | Bill Thomas | Costume Design |
| Sound | Leslie I. Carey | Sound |
| Crew | Gwen Verdon | Choreographer |
| Costume & Make-Up | Bud Westmore | Makeup Artist |
| Art | Russell A. Gausman | Set Decoration |
