A genetically created Anaconda, cut in half, regenerates itself into two new aggressive giant snakes, due to the Blood Orchid.
Unfortunately the movie Anacondas: Trail of Blood is not yet available on HBO Max.
| Writing | David C. Olson | Writer |
| Directing | Don E. FauntLeRoy | Director |
| Costume & Make-Up | Ionel Popa | Special Effects Makeup Artist |
| Camera | Gabriel Kosuth | Second Unit Director of Photography |
| Crew | Lucian Iordache | Special Effects |
| Visual Effects | P.J. Foley | Visual Effects Producer |
| Sound | Steven Avila | Sound Designer |
| Sound | Trip Brock | Supervising Sound Editor |
| Camera | Pãtru Pãunescu | Camera Operator |
| Directing | Roxana Leotescu | Second Assistant Director |
| Camera | Stefan Mangir | Steadicam Operator |
| Directing | Cornelia Stefan | Script Supervisor |
| Sound | Peter D. Lago | Sound Designer |
| Directing | G. Peter King | Second Unit Director |
| Sound | Kyle Tilbury | Sound Re-Recording Mixer |
| Sound | Tom Marks | Sound Re-Recording Mixer |
| Camera | Don E. FauntLeRoy | Director of Photography |
| Production | Phillip B. Goldfine | Executive Producer |
| Costume & Make-Up | Daniela Bușoiu | Key Makeup Artist |
| Costume & Make-Up | Letitia Ghenea | Key Hair Stylist |
| Production | Gillian Hawser | Casting |
| Production | Jeff Gerrard | Casting |
| Crew | Marius Florian | Stunts |
| Crew | Vasile Albineț | Stunt Coordinator |
| Crew | G. Peter King | Stunt Coordinator |
| Crew | Ionel Popa | Special Effects |
| Production | Cristian Bostanescu | Executive In Charge Of Production |
| Lighting | Calin Catalin | Gaffer |
| Visual Effects | James Allan May | VFX Artist |
| Crew | Razvan Gheorghiu | Stunts |
| Crew | Vlad Iacob | Stunts |
| Crew | Florin Stancu | Stunts |
| Crew | Gabi Burlacu | Stunts |
| Art | Gina Calin | Set Decoration |
| Costume & Make-Up | Ana Maria Cucu | Costume Design |
| Production | Benjamin Sacks | Co-Producer |
| Art | Șerban Porupcă | Production Design |
| Production | Bryan S. Sexton | Co-Producer |
| Art | Vlad Roseanu | Art Direction |
| Sound | Peter Meisner | Original Music Composer |
| Production | Vlad Păunescu | Co-Producer |
| Production | Alison Semenza | Producer |
