A mad scientist, Dr. Aranya (Jackie Coogan), has created giant spiders in his Mexican lab in Zarpa Mesa to create a race of superwomen by injecting spiders with human pituitary growth hormones. Women develop miraculous regenerative powers, but men mutate into disfigured dwarves. Spiders grow to human size and intelligence.
Unfortunately the movie Mesa of Lost Women is not yet available on HBO Max.
| Directing | Herbert Tevos | Director |
| Writing | Herbert Tevos | Screenplay |
| Production | Melvin Gordon | Producer |
| Directing | Ron Ormond | Director |
| Sound | Hoyt Curtin | Music |
| Crew | Gilbert Warrenton | Cinematography |
| Crew | Karl Struss | Cinematography |
| Editing | Hugh Winn | Editor |
| Editing | Ray H. Lockert | Editor |
