Young Jeremiah lives in a stable environment with loving foster parents until the day his troubled mother, Sarah, returns to claim him. Jeremiah becomes swept up in his mother's dangerous world of drugs, seedy hotels, strip joints and revolving lovers. Salvation comes in the form of the boy's ultrareligious grandparents, but soon Jeremiah's mother returns. Maternal love binds the pair together on the road until Sarah's desperate and depraved lifestyle finally consumes her.
Unfortunately the movie The Heart Is Deceitful Above All Things is not yet available on HBO Max.
| Writing | Asia Argento | Screenplay |
| Production | Shannon Makhanian | Casting |
| Editing | Jim Mol | Editor |
| Art | Max Biscoe | Production Design |
| Costume & Make-Up | Mel Ottenberg | Costume Design |
| Sound | Morgan | Music |
| Writing | Alessandro Magania | Writer |
| Art | Anuradha Mehta | Set Decoration |
| Sound | Billy Corgan | Music |
| Sound | Kim Gordon | Music |
| Camera | Eric Alan Edwards | Director of Photography |
| Directing | Jennifer Fiedler | First Assistant Director |
| Writing | Laura Albert | Author |
| Directing | Asia Argento | Director |
| Costume & Make-Up | Fleur Morell | Key Makeup Artist |
| Production | Alain de la Mata | Producer |
| Production | David Hillary | Producer |
| Costume & Make-Up | Mel Ottenberg | Hairstylist |
| Costume & Make-Up | Mike Potter | Makeup Artist |
| Production | Lawrence E. Davis | Producer |
| Production | Chris Hanley | Producer |
| Production | Roberta Hanley | Producer |
