Young Jeremiah lives in a stable environment with loving foster parents until the day his troubled mother, Sarah, returns to claim him. Jeremiah becomes swept up in his mother's dangerous world of drugs, seedy hotels, strip joints and revolving lovers. Salvation comes in the form of the boy's ultrareligious grandparents, but soon Jeremiah's mother returns. Maternal love binds the pair together on the road until Sarah's desperate and depraved lifestyle finally consumes her.
Unfortunately the movie The Heart Is Deceitful Above All Things is not yet available on HBO Max.
| Writing | Asia Argento | Screenplay |
| Writing | Alessandro Magania | Writer |
| Editing | Jim Mol | Editor |
| Production | Shannon Makhanian | Casting |
| Art | Max Biscoe | Production Design |
| Art | Anuradha Mehta | Set Decoration |
| Costume & Make-Up | Mel Ottenberg | Costume Design |
| Sound | Kim Gordon | Music |
| Sound | Billy Corgan | Music |
| Sound | Morgan | Music |
| Camera | Eric Alan Edwards | Director of Photography |
| Directing | Jennifer Fiedler | First Assistant Director |
| Writing | Laura Albert | Author |
| Directing | Asia Argento | Director |
| Costume & Make-Up | Mel Ottenberg | Hairstylist |
| Costume & Make-Up | Fleur Morell | Key Makeup Artist |
| Costume & Make-Up | Mike Potter | Makeup Artist |
| Production | Alain de la Mata | Producer |
| Production | Chris Hanley | Producer |
| Production | Lawrence E. Davis | Producer |
| Production | David Hillary | Producer |
| Production | Roberta Hanley | Producer |
