Dr. Frankenstein and her assistant, Dr. Yanco, are going to bring one of their experiments to life in Santo Vs. Frankenstein's Daughter. She intends to use a monster named Ursus to do her evil bidding. Using a youth serum to retain their vitality, the doctors set their sights upon none other than El Santo. They need his super human blood to regenerate a stronger youth serum. They kidnap Santo's goddaughter, Norma and lure him into Dr. Frankenstein's lab where he is captured and enslaved. Will Santo make it out alive?
Unfortunately the movie Santo vs. Frankenstein's Daughter is not yet available on HBO Max.
| Editing | Jorge Busto | Editor |
| Camera | Raúl Martínez Solares | Director of Photography |
| Production | Guillermo Calderón | Producer |
| Production | El Santo | Producer |
| Directing | Miguel M. Delgado | Director |
| Costume & Make-Up | Román Juárez | Makeup Artist |
| Writing | Fernando Osés | Story |
| Art | José Rodríguez Granada | Production Design |
| Sound | Gustavo César Carrión | Music Director |
| Writing | Fernando Osés | Adaptation |
| Editing | Joaquín Ceballos | Assistant Editor |
| Art | Adalberto López | Set Decoration |
