Los Serrano is a Spanish television drama comedy which premiered on 22 April 2003 and aired on Telecinco. It tells the story of the Serrano family, who lives in Round Santa Justa No 133, located in the fictional neighborhood of Santa Justa, in the Ribera del Manzanares, in Madrid. The success of the series in Spain and in several other countries in Europe and elsewhere helped launch the career of several young actors and actresses, especially actor and musician Fran Perea, who acts in the series and sings its theme song, "1 más 1 son 7".
A young widowed doctor tries to rebuild his life and take care of his three children and his teenage nephew. In the house also live his father and the cleaning lady, which marks the rhythm of the day to day life of this family. His sister-in-law, who also plays an important role, will end up marrying him. The series also tells the stories of their colleagues at the health center.