Two police officers, the older Lt. Stone and the young upstart Inspector Keller, investigate murders and other serious crimes in San Francisco. Stone would become a second father to Keller as he learned the rigors and procedures of detective work.
| Title | Air Date | Duration | ||
|---|---|---|---|---|
| Season 1 | Episode 1 | The Streets of San Francisco | 1972-09-16 | 98 min |
| Season 1 | Episode 2 | The Thirty-Year Pin | 1972-09-23 | 60 min |
| Season 1 | Episode 3 | The First Day of Forever | 1972-09-30 | 60 min |
| Season 1 | Episode 4 | 45 Minutes from Home | 1972-10-07 | 60 min |
| Season 1 | Episode 5 | Whose Little Boy Are You? | 1972-10-14 | 60 min |
| Season 1 | Episode 6 | Tower Beyond Tragedy | 1972-10-28 | 60 min |
| Season 1 | Episode 7 | Hall of Mirrors | 1972-11-04 | 60 min |
| Season 1 | Episode 8 | Timelock | 1972-11-11 | 60 min |
| Season 1 | Episode 9 | In the Midst of Strangers | 1972-11-25 | 60 min |
| Season 1 | Episode 10 | The Takers | 1972-12-02 | 60 min |
| Season 1 | Episode 11 | The Year of the Locusts | 1972-12-09 | 60 min |
| Season 1 | Episode 12 | The Bullet | 1972-12-16 | 60 min |
| Season 1 | Episode 13 | Bitter Wine | 1972-12-23 | 60 min |
| Season 1 | Episode 14 | A Trout in the Milk | 1973-01-06 | 60 min |
| Season 1 | Episode 15 | Deathwatch | 1973-01-13 | 60 min |
| Season 1 | Episode 16 | Act of Duty | 1973-01-18 | 60 min |
| Season 1 | Episode 17 | The Set-Up | 1973-01-25 | 60 min |
| Season 1 | Episode 18 | A Collection of Eagles | 1973-02-01 | 60 min |
| Season 1 | Episode 19 | A Room with a View | 1973-02-08 | 60 min |
| Season 1 | Episode 20 | Deadline | 1973-02-15 | 60 min |
| Season 1 | Episode 21 | Trail of the Serpent | 1973-02-22 | 60 min |
| Season 1 | Episode 22 | The House on Hyde Street | 1973-03-01 | 60 min |
| Season 1 | Episode 23 | Beyond Vengeance | 1973-03-08 | 60 min |
| Season 1 | Episode 24 | The Albatross | 1973-03-15 | 60 min |
| Season 1 | Episode 25 | Shattered Image | 1973-03-22 | 60 min |
| Season 1 | Episode 26 | The Unicorn | 1973-04-05 | 60 min |
| Season 1 | Episode 27 | Legion of the Lost | 1973-04-12 | 60 min |
| Season 2 | Episode 1 | A Wrongful Death | 1973-09-13 | 60 min |
| Season 2 | Episode 2 | Betrayed | 1973-09-20 | 60 min |
| Season 2 | Episode 3 | For the Love of God | 1973-09-27 | 60 min |
| Season 2 | Episode 4 | Before I Die | 1973-10-04 | 60 min |
| Season 2 | Episode 5 | Going Home | 1973-10-11 | 60 min |
| Season 2 | Episode 6 | The Stamp of Death | 1973-10-18 | 60 min |
| Season 2 | Episode 7 | Harem | 1973-10-25 | 60 min |
| Season 2 | Episode 8 | No Badge for Benjy | 1973-11-01 | 60 min |
| Season 2 | Episode 9 | The Twenty-Four Karet Plague | 1973-11-08 | 60 min |
| Season 2 | Episode 10 | Shield of Honor | 1973-11-15 | 60 min |
| Season 2 | Episode 11 | The Victims | 1973-11-29 | 60 min |
| Season 2 | Episode 12 | The Runaways | 1973-12-06 | 60 min |
| Season 2 | Episode 13 | Winterkill | 1973-12-13 | 60 min |
| Season 2 | Episode 14 | Most Feared in the Jungle | 1973-12-20 | 60 min |
| Season 2 | Episode 15 | Commitment | 1974-01-03 | 60 min |
| Season 2 | Episode 16 | Chapel of the Damned | 1974-01-17 | 60 min |
| Season 2 | Episode 17 | Blockade | 1974-01-24 | 60 min |
| Season 2 | Episode 18 | Crossfire | 1974-01-31 | 60 min |
| Season 2 | Episode 19 | A String of Puppets | 1974-02-07 | 60 min |
| Season 2 | Episode 20 | Inferno | 1974-02-14 | 60 min |
| Season 2 | Episode 21 | The Hard Breed | 1974-02-21 | 60 min |
| Season 2 | Episode 22 | Rampage | 1974-02-28 | 60 min |
| Season 2 | Episode 23 | Death and the Favored Few | 1974-03-14 | 60 min |
| Season 3 | Episode 1 | One Last Shot | 1974-09-12 | 60 min |
| Season 3 | Episode 2 | The Most Deadly Species | 1974-09-19 | 60 min |
| Season 3 | Episode 3 | Target: Red | 1974-09-26 | 60 min |
| Season 3 | Episode 4 | Mask of Death | 1974-10-03 | 60 min |
| Season 3 | Episode 5 | I Ain't Marchin' Anymore | 1974-10-10 | 60 min |
| Season 3 | Episode 6 | One Chance to Live | 1974-10-17 | 60 min |
| Season 3 | Episode 7 | Jacob's Boy | 1974-10-24 | 60 min |
| Season 3 | Episode 8 | Flags of Terror | 1974-10-31 | 60 min |
| Season 3 | Episode 9 | Cry Help! | 1974-11-07 | 60 min |
| Season 3 | Episode 10 | For Good or Evil | 1974-11-14 | 60 min |
| Season 3 | Episode 11 | Bird of Prey | 1974-11-21 | 60 min |
| Season 3 | Episode 12 | License to Kill | 1974-12-05 | 60 min |
| Season 3 | Episode 13 | The Twenty-Five Caliber Plague | 1974-12-12 | 60 min |
| Season 3 | Episode 14 | Mister Nobody | 1974-12-19 | 60 min |
| Season 3 | Episode 15 | False Witness | 1975-01-09 | 60 min |
| Season 3 | Episode 16 | Letters from the Grave | 1975-01-16 | 60 min |
| Season 3 | Episode 17 | Endgame | 1975-01-23 | 60 min |
| Season 3 | Episode 18 | Ten Dollar Murder | 1975-01-30 | 60 min |
| Season 3 | Episode 19 | The Programming of Charlie Blake | 1975-02-06 | 60 min |
| Season 3 | Episode 20 | River of Fear | 1975-02-13 | 60 min |
| Season 3 | Episode 21 | Asylum | 1975-02-20 | 60 min |
| Season 3 | Episode 22 | Labyrinth | 1975-02-27 | 60 min |
| Season 3 | Episode 23 | Solitaire | 1975-03-13 | 60 min |
| Season 4 | Episode 1 | Poisoned Snow | 1975-09-11 | 60 min |
| Season 4 | Episode 2 | The Glass Dart Board | 1975-09-18 | 60 min |
| Season 4 | Episode 3 | No Place to Hide | 1975-09-25 | 60 min |
| Season 4 | Episode 4 | Men Will Die | 1975-10-02 | 60 min |
| Season 4 | Episode 5 | School of Fear | 1975-10-09 | 60 min |
| Season 4 | Episode 6 | Deadly Silence | 1975-10-16 | 60 min |
| Season 4 | Episode 7 | Murder by Proxy | 1975-10-23 | 60 min |
| Season 4 | Episode 8 | Trail of Terror | 1975-10-30 | 60 min |
| Season 4 | Episode 9 | Web of Lies | 1975-11-06 | 60 min |
| Season 4 | Episode 10 | Dead Air | 1975-11-13 | 60 min |
| Season 4 | Episode 11 | Merchants of Death | 1975-11-20 | 60 min |
| Season 4 | Episode 12 | The Cat's Paw | 1975-12-04 | 60 min |
| Season 4 | Episode 13 | Spooks for Sale | 1975-12-11 | 60 min |
| Season 4 | Episode 14 | Most Likely to Succeed | 1975-12-18 | 60 min |
| Season 4 | Episode 15 | Police Buff | 1976-01-08 | 60 min |
| Season 4 | Episode 16 | The Honorable Profession | 1976-01-15 | 60 min |
| Season 4 | Episode 17 | Requiem for Murder | 1976-01-22 | 60 min |
| Season 4 | Episode 18 | Underground | 1976-01-29 | 60 min |
| Season 4 | Episode 19 | Judgment Day | 1976-02-19 | 60 min |
| Season 4 | Episode 20 | Clown of Death | 1976-02-26 | 60 min |
| Season 4 | Episode 21 | Superstar | 1976-03-04 | 60 min |
| Season 4 | Episode 22 | Alien Country | 1976-03-11 | 60 min |
| Season 4 | Episode 23 | Runaway | 1976-03-18 | 60 min |
| Season 5 | Episode 1 | The Thrill Killers (1) | 1976-09-30 | 60 min |
| Season 5 | Episode 2 | The Thrill Killers (2) | 1976-10-07 | 60 min |
| Season 5 | Episode 3 | Dead or Alive | 1976-10-21 | 60 min |
| Season 5 | Episode 4 | The Drop | 1976-10-28 | 60 min |
| Season 5 | Episode 5 | No Minor Vices | 1976-11-04 | 60 min |
| Season 5 | Episode 6 | In Case of Madness | 1976-11-11 | 60 min |
| Season 5 | Episode 7 | Till Death Do Us Part | 1976-11-18 | 60 min |
| Season 5 | Episode 8 | Child of Anger | 1976-12-02 | 60 min |
| Season 5 | Episode 9 | Hot Dog | 1976-12-09 | 60 min |
| Season 5 | Episode 10 | Castle of Fear | 1976-12-23 | 60 min |
| Season 5 | Episode 11 | One Last Trick | 1977-01-06 | 60 min |
| Season 5 | Episode 12 | Monkey is Back | 1977-01-13 | 60 min |
| Season 5 | Episode 13 | The Cannibals | 1977-01-20 | 60 min |
| Season 5 | Episode 14 | Who Killed Helen French? | 1977-02-03 | 60 min |
| Season 5 | Episode 15 | A Good Cop...But | 1977-02-10 | 60 min |
| Season 5 | Episode 16 | Hang Tough | 1977-02-17 | 60 min |
| Season 5 | Episode 17 | Innocent No More | 1977-02-24 | 60 min |
| Season 5 | Episode 18 | Once a Con | 1977-03-03 | 60 min |
| Season 5 | Episode 19 | Interlude | 1977-04-28 | 60 min |
| Season 5 | Episode 20 | Dead Lift | 1977-05-05 | 60 min |
| Season 5 | Episode 21 | Breakup | 1977-05-12 | 60 min |
| Season 5 | Episode 22 | Let's Pretend We're Strangers | 1977-05-19 | 60 min |
| Season 5 | Episode 23 | Time Out | 1977-06-02 | 60 min |
| Season 5 | Episode 24 | The Canine Collar | 1977-06-09 | 60 min |
| Production | Quinn Martin | Executive Producer |
| Production | William Robert Yates | Producer |
| Sound | Patrick Williams | Main Title Theme Composer |
