William Masters and Virginia Johnson are real-life pioneers of the science of human sexuality. Their research touched off the sexual revolution and took them from a midwestern teaching hospital to the cover of Time magazine and multiple appearances on Johnny Carson's couch. He is a brilliant scientist out of touch with his own feelings, and she is a single working mother ahead of her time. The series chronicles their unusual lives, romance, and unlikely pop culture trajectory.
| Title | Air Date | Duration | ||
|---|---|---|---|---|
| Season 1 | Episode 1 | Pilot | 2013-09-29 | 60 min |
| Season 1 | Episode 2 | Race to Space | 2013-10-06 | 60 min |
| Season 1 | Episode 3 | Standard Deviation | 2013-10-13 | 60 min |
| Season 1 | Episode 4 | Thank You for Coming | 2013-10-20 | 60 min |
| Season 1 | Episode 5 | Catherine | 2013-10-27 | 60 min |
| Season 1 | Episode 6 | Brave New World | 2013-11-03 | 60 min |
| Season 1 | Episode 7 | All Together Now | 2013-11-10 | 60 min |
| Season 1 | Episode 8 | Love and Marriage | 2013-11-17 | 60 min |
| Season 1 | Episode 9 | Involuntary | 2013-11-24 | 60 min |
| Season 1 | Episode 10 | Fallout | 2013-12-01 | 60 min |
| Season 1 | Episode 11 | Phallic Victories | 2013-12-08 | 60 min |
| Season 1 | Episode 12 | Manhigh | 2013-12-15 | 60 min |
| Season 2 | Episode 1 | Parallax | 2014-07-13 | 60 min |
| Season 2 | Episode 2 | Kyrie Eleison | 2014-07-20 | 60 min |
| Season 2 | Episode 3 | Fight | 2014-07-27 | 60 min |
| Season 2 | Episode 4 | Dirty Jobs | 2014-08-03 | 60 min |
| Season 2 | Episode 5 | Giants | 2014-08-10 | 60 min |
| Season 2 | Episode 6 | Blackbird | 2014-08-17 | 60 min |
| Season 2 | Episode 7 | Asterion | 2014-08-24 | 60 min |
| Season 2 | Episode 8 | Mirror, Mirror | 2014-08-31 | 60 min |
| Season 2 | Episode 9 | Story of My Life | 2014-09-07 | 60 min |
| Season 2 | Episode 10 | Below the Belt | 2014-09-14 | 60 min |
| Season 2 | Episode 11 | One for the Money, Two for the Show | 2014-09-21 | 60 min |
| Season 2 | Episode 12 | The Revolution Will Not Be Televised | 2014-09-28 | 60 min |
| Season 3 | Episode 1 | Parliament of Owls | 2015-07-12 | 60 min |
| Season 3 | Episode 2 | Three's a Crowd | 2015-07-19 | 60 min |
| Season 3 | Episode 3 | The Excitement of Release | 2015-07-26 | 60 min |
| Season 3 | Episode 4 | Undue Influence | 2015-08-02 | 60 min |
| Season 3 | Episode 5 | Matters of Gravity | 2015-08-09 | 60 min |
| Season 3 | Episode 6 | Two Scents | 2015-08-16 | 60 min |
| Season 3 | Episode 7 | Monkey Business | 2015-08-23 | 60 min |
| Season 3 | Episode 8 | Surrogates | 2015-08-30 | 60 min |
| Season 3 | Episode 9 | High Anxiety | 2015-09-06 | 60 min |
| Season 3 | Episode 10 | Through a Glass, Darkly | 2015-09-13 | 60 min |
| Season 3 | Episode 11 | Party of Four | 2015-09-20 | 60 min |
| Season 3 | Episode 12 | Full Ten Count | 2015-09-27 | 60 min |
| Season 4 | Episode 1 | Freefall | 2016-09-11 | 60 min |
| Season 4 | Episode 2 | Inventory | 2016-09-18 | 60 min |
| Season 4 | Episode 3 | The Pleasure Protocol | 2016-09-25 | 60 min |
| Season 4 | Episode 4 | Coats or Keys | 2016-10-02 | 60 min |
| Season 4 | Episode 5 | Outliers | 2016-10-09 | 60 min |
| Season 4 | Episode 6 | Family Only | 2016-10-16 | 60 min |
| Season 4 | Episode 7 | In to Me You See | 2016-10-23 | 60 min |
| Season 4 | Episode 8 | Topeka | 2016-10-30 | 60 min |
| Season 4 | Episode 9 | Night and Day | 2016-11-06 | 60 min |
| Season 4 | Episode 10 | The Eyes of God | 2016-11-13 | 60 min |
| Production | Michelle Ashford | Executive Producer |
| Production | Sarah Timberman | Executive Producer |
| Production | Carl Beverly | Executive Producer |
| Production | Amy Lippman | Executive Producer |
| Production | Judith Verno | Executive Producer |
| Writing | Thomas Maier | Novel |
